EU reference date; synonym: Union reference date

For medicinal products containing the same active substance or the same combination of active substances, the date of the first marketing authorisation in the EU of a medicinal product containing that active substance or that combination of active substances; or if this date cannot be ascertained, the earliest of the known dates of the marketing authorisations for a medicinal product containing that active substance or that combination of active substances [DIR 2001/83/EC Art 107c(5)].